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allergy to cats
Cat allergy in humans is an allergic reaction to one or more allergens produced by cats. The most common of these allergens are the glycoprotein Fel d 1, secreted by the cat's sebaceous glands and Fel d 4, which is expressed in saliva. An allergic reaction is a histamine reaction that is usually characterized by coughing, wheezing, chest tightening, itching, nasal congestion, rash, watering eyes, sneezing, chapped lips, and similar symptoms.
== Cat allergens ==
Five cat allergens have been described in medical literature. The two major allergens are Fel d 1 (a secretoglobin) and Fel d 4 (a lipocalin). The minor allergens include Fel d 2 (an albumin), Fel d 3 (a cystatin), and cat IgA.〔Adédoyin J, et al. ("Cat IgA, representative of new carbohydrate cross-reactive allergens" ) ''The Journal of Allergy and Clinical Immunology'', 2007-3. Retrieved on 2009-8-1.〕
Fel d 4 is the product of the cat major urinary protein gene. It is primarily expressed in the submandibular salivary gland and is deposited onto dander as the cat grooms itself. A study found that 63% of cat allergic people have antibodies against Fel d 4.
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
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